Careers

TALENT DRIVES SUCCESS

We are looking for exceptionally talented individuals who share our passion for revolutionary science and commitment to changing the world by helping patients with serious diseases. We provide competitive and comprehensive benefits and are making REVOLUTION Medicines a great place to work.

CURRENT POSITIONS

REVOLUTION Medicines is an exciting, early stage biotechnology company that discovers and develops innovative drugs for cancer patients directed toward frontier oncology and immune-oncology targets.  The company draws inspiration from evolution and natural products that are inherently rich with biological function. REVOLUTION Medicines deploys an innovative toolkit including REVBLOCKS™, an integrated suite of rapid, agile, and modular synthesis methodologies applied to simple chemical “building blocks,” and the REVEAL™ computational platform, which uses evolution’s lessons to inform selection of chemical scaffolds guide drug design for non-classical drug targets. As a new member of the RevMed team, you will join other outstanding scientists who are helping lead our efforts in the discovery and development of new medicines for unmet needs in cancer.

The Opportunity:

As a key player in our biology team, you will:

  • Contribute to scientific and operational strategies for ongoing and exploratory cancer programs

  • Perform cutting-edge cell biology research by integrating knowledge from oncology, immunology and human genetics to support development of novel therapies, using innovative technologies and approaches

  • Independently conceive and execute experimental strategies to identify/validate novel oncology and immuno-oncology targets, and to elucidate the mechanism of action of investigational compounds.

  • Create translational plans to support early development of potential drug candidates

  • As a member of a cross-functional project team, collaborate with chemists, biologists and pharmacologists to generate novel insights that fuel drug development

  • Establish collaborations with leading academic research groups and CROs

  • Represent REVOLUTION Medicines with external organizations

 

Required Experience, Skills, and Education:

  • Ph.D. degree in cell biology, oncology, cellular immunology or a related discipline and post-doctoral and/or 2+ years relevant industry experience

  • Strong track record of research productivity as evidenced by high-quality, impactful publications

  • Thrives in a collaborative team setting and is driven by a desire to innovative in a high energy start-up environment

  • Hands-on experience with a wide range of molecular, cellular and computational techniques that would be suitable for target identification/characterization, including development of human cell- and tissue-based assays, CRISPR gene editing, as well as general technical innovation

  • Deep expertise in oncogenic signaling pathways would be an advantage

  • Rigorous, quantitative and detail-oriented experimentalist

  • Excellent written and verbal communication skills

  • Demonstrated ability to multi-task, prioritize options, anticipate challenges, and execute on goals as a member of an interdisciplinary team is extremely important

REVOLUTION Medicines is an exciting, early stage biotechnology company that discovers and develops innovative drugs for cancer patients directed toward frontier oncology and immune-oncology targets.  The company draws inspiration from evolution and natural products that are inherently rich with biological function. REVOLUTION Medicines deploys an innovative toolkit including REVBLOCKS™, an integrated suite of rapid, agile, and modular synthesis methodologies applied to simple chemical “building blocks,” and the REVEAL™ computational platform, which uses evolution’s lessons to inform selection of chemical scaffolds guide drug design for non-classical drug targets. As a new member of the RevMed team, you will join other outstanding scientists who are helping lead our efforts in the discovery and development of new medicines for unmet needs in cancer.

The Opportunity:

As a leader of cancer biology you will:

  • Collaborate with senior leaders in the company to refine our cancer discovery biology vision and to develop scientific and operational strategies accordingly.
  • Prosecute cutting-edge cancer biology research, integrating knowledge from oncology, immunology and human genetics to support development of novel therapies using innovative technologies and approaches.

  • Spearhead strategies, including the application of genetic and/or computational methods, to identify/validate novel oncology and immuno-oncology pathways and targets and to elucidate the mechanism of action of investigational compounds.

  • Apply strong scientific, technical, and organizational leadership skills to the development of lead discovery strategies for multiple programs

  • Work cross-functionally to create translational plans to support early clinical development of potential drug candidates.

  • In the context of cross-functional project teams collaborate with chemists, biologists and pharmacologists to generate novel insights that fuel drug development.

  • Establish collaborations with leading academic cancer research groups and CROs.

  • Represent REVOLUTION Medicines with external organizations.

 

Required Experience, Skills, and Education:

  • Ph.D. degree in cell biology, oncology, cellular immunology or a related discipline, with at least 5+ years of post-doctoral and relevant industry experience in cancer discovery biology from target selection to late preclinical evaluation.

  • Strategic, creative, innovative, and motivated by building a team; thrives in a collaborative environment.

  • Proven leadership skills with direct line management responsibilities, and/or project team leadership roles.

  • Experience working with external collaborators in cancer biology field in basic and/or clinical science

  • Strong track record of research productivity as evidenced by high-quality, impactful publications.

  • Rigorous, quantitative and detail-oriented experimentalist.

  • Excellent written and verbal communication skills.

  • Demonstrated ability to multi-task, prioritize options, anticipate challenges, and execute on goals as a member of an interdisciplinary team is extremely important.

  • Innovative, generous team-player with enthusiasm for our start-up environment.

REVOLUTION Medicines is an exciting, early stage biotechnology company that discovers and develops innovative drugs for cancer patients directed toward frontier oncology and immune-oncology targets.  The company draws inspiration from evolution and natural products that are inherently rich with biological function. REVOLUTION Medicines deploys an innovative toolkit including REVBLOCKS™, an integrated suite of rapid, agile, and modular synthesis methodologies applied to simple chemical “building blocks,” and the REVEAL™ computational platform, which uses evolution’s lessons to inform selection of chemical scaffolds guide drug design for non-classical drug targets. As a new member of the RevMed team, you will join other outstanding scientists who are helping lead our efforts in the discovery and development of new medicines for unmet needs in cancer.

The Opportunity:

As a key member of the Chemistry team, you will: 

  • Have a fresh, dynamic and “can-do” attitude.  You will be a role model for leading from the bench with respect to high quality compound design through to synthesis execution
  • Analyze project data and communicate findings and recommendations to a variety of stakeholders 

  • Partner in the scientific activities of other outstanding medicinal chemists in the department and help create an environment where we channel scientific curiosity to build and deliver a sustainable portfolio

  • Substantially contribute to the conception and implementation of innovative, interdisciplinary research projects

  • Represent REVOLUTION Medicines with external organizations and help build the scientific reputation for our novel Drug Discovery paradigm through a variety of external disclosures

  • Enhance our operational efficiency & flexibility through continuous improvement activities and implementation of best practice

  • Embrace all sources of innovation to improve project success rates and expand our target space 

  • Secure our junior chemists future scientific & career growth through high quality coaching and mentoring

  • Demonstrate commitment to the RevMed chemistry department vision to ensure we are acknowledged both internally & externally as the “next generation” natural product-inspired Medicinal Chemistry specialists

  • Be instrumental in the successfully delivery of a range of anti-cancer Drug Candidates for frontier oncology targets

 

Required Experience, Skills, and Education:

  • Ph.D. degree in chemistry with a deep understanding of medicinal and synthetic chemistry, from hit generation through to candidate selection

  • Ideally 5+ years of drug discovery experience with a strong track record of scientific leadership, innovation and candidate drug delivery

  • Excellent written and verbal communication skills to work with interdepartmental teams

  • Innovative team-player with high energy for our start-up environment

  • Demonstrated ability to lead, plan and achieve research goals as part of an interdisciplinary team

REVOLUTION Medicines is an exciting, early stage biotechnology company that discovers and develops innovative drugs for cancer patients directed toward frontier oncology and immune-oncology targets.  The company draws inspiration from evolution and natural products that are inherently rich with biological function. REVOLUTION Medicines deploys an innovative toolkit including REVBLOCKS™, an integrated suite of rapid, agile, and modular synthesis methodologies applied to simple chemical “building blocks,” and the REVEAL™ computational platform, which uses evolution’s lessons to inform selection of chemical scaffolds guide drug design for non-classical drug targets. As a new member of the RevMed team, you will join other outstanding scientists who are helping lead our efforts in the discovery and development of new medicines for unmet needs in cancer.

The Opportunity:

As a key player on our preclinical pharmacology team, you will:

  • Help to design and manage in vivo and ex vivo experiments conducted at contract research organizations (CROs) related to the discovery of novel anti-cancer agents.

  • Approach novel oncology/immuno-oncology target validation and development through design of appropriate preclinical studies.

  • Establish and validate preclinical in vivo Pharmacokinetic (PK)/Pharmacodynamic (PD) preclinical oncology studies. Help to relate exposures of small molecules and PD to efficacy toward inhibition of tumor growth (and possibly alteration in immune markers) in animal models.

  • Develop and validate appropriate preclinical biomarkers and apply learnings toward development of potential clinical biomarkers.

  • Manage screening efforts of test articles through appropriate animal models. Work closely with colleagues in Medicinal Chemistry, Biology and DMPK to identify, characterize, and prioritize molecules.

  • Manage and analyze experimental data and present experimental results at internal meetings and scientific conferences.

  • Develop protocols and maintain detailed documentation of procedures and data.

 

 Required Experience, Skills, and Education:

  • A DVM or Ph.D. in Pharmacology, Physiology, Biology, or a related discipline with 1-3 years of postdoctoral experience and at least 3 years’ experience in the biopharmaceutical industry.

  • Established knowledgebase in at least one aspect of cancer-related biology or immunology.

  • Experience in establishing and executing oncology-related disease models.

  • Experience with experimental design, data analysis methods, data management, and presentation.

  • Experience preparing documents supporting regulatory submissions is helpful.

  • Excellent verbal and written communication skills.

  • Demonstrated ability to multi-task, prioritize options, anticipate challenges, and execute on goals as a member of multidisciplinary project teams is extremely important.

  • Thrives in a collaborative team setting and is driven by a desire to be innovative in a high energy start-up environment.

JOIN THE REVOLUTION!

We offer a dynamic, collaborative and scientifically challenging environment plus an excellent benefits package. To be considered for one of these exciting career opportunities, please forward your resume with a cover letter to talent@revolutionmedicines.com.

REVOLUTION Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status.

Note to Employment Agencies: Please do not forward any agency resumes as REVOLUTION Medicines is not responsible for any fees related to resumes that are unsolicited.