Revolution Medicines - 2015 Fierce 15

The scoop: As drug discovery platforms go, none is older than evolution. Over billions of years, the slow march of life has brought about natural agents gradually selected for their ability to modulate certain biological processes. But evolution's products, however elegant, don't often come out of the gate with the tolerability and specificity required for medicinal use. That's where startup Revolution Medicines comes in, developing a technology through which it can break down natural compounds to their composite parts, apply some chemistry know-how and then reassemble them into usable drugs.

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